Protein StatusUpdated 2025-12-24Medically Reviewed
Prealbumin (Transthyretin)
Everything you need to know about Prealbumin (Transthyretin) levels, including what normal ranges look like and what abnormal results might indicate.
Standard Reference Range
Unit: mg/dLMale Reference Range
18–45 mg/dL
Female Reference Range
18–45 mg/dL
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Reference ranges may vary slightly between laboratories. Always consult your doctor for interpretation.
What is Prealbumin?
Prealbumin is a short–half-life transport protein for thyroid hormone and vitamin A. Because it turns over quickly, it reflects recent protein-calorie nutrition and acute inflammation.
Key Takeaway
Low prealbumin can mean malnutrition—or simply inflammation; check CRP to interpret correctly.
Why is this test performed?
- Monitor short-term nutritional status or response to feeding
- Evaluate protein loss in illness, surgery, or chronic disease
- Track recovery in hospitalized or critically ill patients
Interpreting Your Results
- Low: Malnutrition, liver disease, inflammation (CRP high), protein-losing states
- High: Rare; may rise with high-dose steroids or dehydration
Related Tests
- Albumin/Total Protein: Longer-term protein status
- CRP: Distinguishes inflammation-driven drop
- Bilirubin: Another liver synthesis marker
Decode your Prealbumin Results
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