LDH (Lactate Dehydrogenase)
Everything you need to know about LDH (Lactate Dehydrogenase) levels, including what normal ranges look like and what abnormal results might indicate.
Standard Reference Range
Unit: U/LReference ranges may vary slightly between laboratories. Always consult your doctor for interpretation.
What is LDH?
Lactate Dehydrogenase (LDH) is an enzyme present in nearly all body tissues. When cells are damaged—whether in the heart, liver, muscles, lungs, or blood—LDH leaks into the bloodstream, making it a broad marker of tissue injury.
Key Takeaway
LDH is sensitive but not specific: elevations signal cell damage but do not pinpoint the organ without other tests.
Why is this test performed?
- Screen for hemolysis or tissue breakdown
- Aid diagnosis of heart attack or pulmonary embolism (with other markers)
- Monitor cancers (e.g., lymphoma) for tumor burden
- Track recovery after major muscle injury or surgery
Interpreting Your Results
Elevated LDH
- Hemolysis: Often paired with high indirect bilirubin and low haptoglobin
- Liver injury: Accompanies rises in AST/ALT
- Muscle injury: Check CK to localize to muscle
- Lung/Heart stress: May rise in pulmonary embolism or heart attack
- Cancer activity: Elevated in many aggressive tumors
Normal or Low LDH
Typically not concerning; low values have minimal clinical use.
Related Tests
- AST/ALT: Help localize liver injury
- CK: Distinguishes muscle damage from other causes
- Bilirubin: Elevates with hemolysis or cholestasis
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