Liver FunctionUpdated 2025-12-24Medically Reviewed
Direct (Conjugated) Bilirubin
Everything you need to know about Direct (Conjugated) Bilirubin levels, including what normal ranges look like and what abnormal results might indicate.
Standard Reference Range
Unit: mg/dLMale Reference Range
0.0–0.3 mg/dL
Female Reference Range
0.0–0.3 mg/dL
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Reference ranges may vary slightly between laboratories. Always consult your doctor for interpretation.
What is Direct Bilirubin?
Direct (conjugated) bilirubin is bilirubin that the liver has processed for excretion into bile. It rises when bile cannot flow properly or when liver cells cannot secrete bile.
Key Takeaway
Elevated direct bilirubin points toward cholestasis (bile flow problem) rather than hemolysis.
Why is this test performed?
- Clarify cause of jaundice
- Detect bile duct obstruction (stones, tumors)
- Monitor cholestatic liver diseases and drug reactions
Interpreting Your Results
- High Direct with Normal Indirect: Obstruction or cholestasis
- High Both: Mixed liver injury or severe hepatitis
Related Tests
- ALT/AST: Hepatocellular injury
- ALP/GGT: Bile duct obstruction markers
- Total Bilirubin: Combines direct and indirect fractions
Decode your Direct Bilirubin Results
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