Avascular Necrosis of the Hip on MRI
Understand Avascular Necrosis of the Hip on MRI in Hip Magnetic Resonance Imaging imaging, what it means, and next steps.
30-Second Overview
Subchondral serpiginous low-signal rim with inner high T2 signal (double-line sign); marrow edema in early stages; subchondral fracture/collapse indicates advanced disease
MRI is the most sensitive imaging modality for early AVN detection, showing changes before X-rays. Findings stage disease and guide hip preservation vs replacement decisions. Early detection enables interventions that may prevent collapse.
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Imaging Appearance
Magnetic Resonance Imaging FindingSubchondral serpiginous low-signal rim with inner high T2 signal (double-line sign); marrow edema in early stages; subchondral fracture/collapse indicates advanced disease
Clinical Significance
MRI is the most sensitive imaging modality for early AVN detection, showing changes before X-rays. Findings stage disease and guide hip preservation vs replacement decisions. Early detection enables interventions that may prevent collapse.
What You'll See on Your MRI
Before understanding what avascular necrosis (AVN) looks like on an MRI, let's review some important context about this potentially devastating hip condition.
MRI can detect AVN months before X-rays show any changes, giving patients a crucial window for hip-preserving treatments before collapse occurs
Think of your femoral head (the ball of your hip ball-and-socket joint) as living bone that needs a constant blood supply. When that blood supply is disrupted, the bone begins to die. This is avascular necrosis, also called osteonecrosis. Without early treatment, the dead bone can collapse, leading to severe arthritis and the need for hip replacement.
Here are the key statistics about MRI accuracy for hip AVN:
Detects AVN months before X-ray changes
Correctly rules out healthy patients
Annual new cases
Understanding Avascular Necrosis
AVN occurs when blood flow to the femoral head is disrupted, causing bone cell death. Without intervention, the dead bone cannot maintain structural integrity and may collapse.
Causes of Blood Flow Disruption:
- Trauma: Hip fracture or dislocation damages blood vessels
- Corticosteroids: High-dose or long-term use (most common non-traumatic cause)
- Alcohol abuse: Direct toxic effect on bone cells and fat cell accumulation
- Sickle cell disease: Sickled cells block blood vessels
- Other conditions: Lupus, HIV, organ transplantation, diving disorders
Stages of AVN (Ficat and ARCO Classification):
- Stage 0: Normal X-ray, abnormal MRI (earliest detection)
- Stage I: Normal X-ray, MRI changes present
- Stage II: X-ray shows sclerosis or cysts, no collapse
- Stage III: Subchondral collapse or crescent sign
- Stage IV: Flattening of femoral head, joint space narrowing
- Stage V: Advanced arthritis
Symptoms:
- Groin or buttock pain
- Pain worse with weight bearing
- Pain that may radiate down the thigh
- Limping
- Limited range of motion
- Eventually, pain even at rest
How It Appears on Imaging
Let's compare what a normal hip looks like versus what AVN looks like on an MRI:
What a Normal Hip Looks Like
The femoral head shows uniform marrow signal throughout. The articular cartilage is smooth and intact. The acetabulum (socket) has normal cartilage thickness. No bone marrow edema is present. The joint space is preserved. The surrounding muscles and soft tissues appear normal.
What AVN Looks Like
Early AVN shows geographic area of bone marrow edema (T2 hyperintensity) in the anterosuperior femoral head. The classic 'double-line sign' appears on T2: a low-signal outer rim (sclerotic bone) with inner high signal (granulation tissue). Advanced disease shows subchondral fracture, crescent-shaped low signal, femoral head flattening, collapse, and joint effusion.
Key Findings Pattern
When interpreting an MRI for hip AVN, radiologists assess specific features that guide treatment:
Key Imaging Findings
Double-line sign
Characteristic finding on T2-weighted images: a serpiginous low-signal outer rim (sclerotic reactive bone) surrounding a high-signal inner rim (granulation tissue). Pathognomonic for AVN
Geographic marrow edema
Well-defined area of T1 hypointensity and T2 hyperintensity in the femoral head, typically in the anterosuperior weight-bearing region. Represents early ischemic necrosis
Subchondral fracture
Low-signal line beneath the articular surface representing fracture through necrotic bone. May appear as a crescent-shaped lucency (crescent sign)
Femoral head collapse
Flattening or loss of spherical contour of the femoral head. May be focal (early) or generalized (advanced). Associated with joint effusion and cartilage loss
Contrast enhancement patterns
With gadolinium, the necrotic region shows no enhancement (avascular) while surrounding reactive tissue shows enhancement. Helps delineate the extent of necrosis
When Your Doctor Orders This Test
Here's a typical clinical scenario where an MRI is ordered for suspected hip AVN:
Clinical Scenario
Your doctor might order an MRI for suspected hip AVN if you have:
| Symptom | Why It Matters | |---------|----------------| | Persistent hip pain with normal X-ray | MRI detects AVN months before X-ray | | Risk factors (steroids, alcohol) | High risk for developing AVN | | Pain in groin or buttock | Classic referred pain pattern from hip | | Pain worse with weight bearing | Suggests mechanical problem in hip joint | | Limited range of motion | Indicates hip joint pathology |
What Else Could It Be?
Not every hip pain with bone marrow edema is AVN. Here's what else could be causing similar findings:
Not All Bone Marrow Edema Is AVN
Transient osteoporosis, stress fractures, and early arthritis can mimic AVN on MRI. Clinical history and specific MRI patterns help distinguish these conditions.
What Else Could It Be?
MRI shows geographic lesion in femoral head with double-line sign. Classic anterosuperior location. Risk factors present (steroids, alcohol). Well-defined margins.
Diffuse bone marrow edema without well-defined margins. No double-line sign. Self-limiting, resolves within 6-12 months. More common in pregnancy and middle-aged men.
Low-signal fracture line parallel to subchondral bone, usually without the diffuse necrosis pattern of AVN. More common in elderly osteoporotic patients.
Cartilage loss, osteophytes, joint space narrowing. Bone marrow edema may be present but lacks the geographic pattern of AVN.
Joint effusion, synovial enhancement, bone marrow edema. Clinical presentation with fever, elevated inflammatory markers. Requires urgent diagnosis.
How Accurate Is This Test?
The evidence for MRI in hip AVN diagnosis shows excellent performance:
AVN affects both hips in half of patients. MRI of the contralateral hip is routinely performed even if asymptomatic, to detect early disease.
Your MRI shows a geographic area in the femoral head with a serpiginous low-signal outer rim and inner high T2 signal. What does this most likely represent?
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What Happens Next?
If your MRI confirms hip AVN, here's what to expect:
What Happens Next?
Your doctor receives the MRI report
The radiologist stages the AVN (0-IV), estimates the percentage of femoral head involved, assesses for collapse or subchondral fracture, and examines the contralateral hip (affected in 50% of cases).
Orthopedic surgery consultation
Evaluation by an orthopedic hip specialist to discuss treatment options based on stage: early disease may be treated with hip-preserving procedures, while advanced disease may require hip replacement.
Hip-preserving procedures (early AVN without collapse)
Core decompression (drilling into femoral head to relieve pressure and promote healing), possibly with bone graft or stem cells. Best results in stages I-II.
Total hip replacement (advanced AVN with collapse)
Removing damaged femoral head and replacing with prosthesis. Highly successful for pain relief. Return to normal activities in 2-3 months.
Contralateral hip screening
MRI of the opposite hip is recommended since AVN is bilateral in 50% of cases. Early detection of asymptomatic disease allows preventive treatment.
When to Seek Urgent Care
Seek prompt orthopedic evaluation if you experience:
- Sudden inability to bear weight on the affected leg
- Severe hip pain after a minor injury (possible fracture through weakened bone)
- Rapidly worsening pain or new onset of pain at night
- Sudden locking or catching sensation in the hip
Prognosis and Treatment Outcomes
Early AVN (Stages I-II, no collapse):
- Core decompression success: 60-80%
- Best results when < 15% of femoral head involved
- Combined with bone grafting: improved outcomes
- Without treatment: > 80% progress to collapse
Advanced AVN (Stages III-IV, collapse present):
- Core decompression less effective
- Usually requires total hip replacement
- THR outcomes: excellent pain relief, 95% patient satisfaction
- Prosthesis longevity: 15-20+ years in most patients
Bilateral Disease:
- Present in 50% at diagnosis
- Need for eventual bilateral surgery in 30-40%
- Sequential rather than simultaneous surgery typically
Risk Factors for Progression:
- Larger necrotic area (> 30% of femoral head)
- Involvement of weight-bearing region
- Continued corticosteroid use
- Alcohol use
- Advanced stage at diagnosis
Frequently Asked Questions
Can AVN heal without surgery?
In very early stages (Stage 0-I), some cases may stabilize with conservative treatment (medication, protected weight bearing), but most progress. Core decompression in early stages provides the best chance of preventing collapse and avoiding hip replacement.
Will I need a hip replacement?
Not necessarily. If AVN is detected early (before collapse), hip-preserving procedures like core decompression may prevent the need for replacement. However, once collapse occurs, hip replacement is usually the most reliable treatment.
How long does it take for AVN to progress?
From early AVN to collapse typically takes 6 months to 2 years, but this varies. Some progress rapidly (months), others slowly (years). Regular MRI monitoring helps track progression.
Can AVN be prevented?
If you have risk factors (especially corticosteroids), some preventive measures may help: limit steroid dose and duration, avoid alcohol, treat underlying conditions, consider bisphosphonates (controversial), and maintain bone health with calcium/vitamin D.
What is core decompression?
Core decompression is a minimally invasive surgery where one or more holes are drilled into the femoral head. This relieves pressure inside the bone, improves blood flow, and creates channels for new blood vessels to form. Combined with bone grafting in some cases.
References
Medical References
This content is referenced from authoritative medical organizations:
- 1.
- 2.
- 3.MRI Diagnosis of Hip Osteonecrosis— Radiological Society of North America(2023)
Medical Disclaimer: This information is for educational purposes. Always discuss your imaging results with your orthopedic surgeon or healthcare provider for personalized medical advice.
Correlate with Lab Results
When Avascular Necrosis of the Hip on MRI appears on imaging, doctors often check these lab tests:
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