Semaglutide

What is Semaglutide?

Semaglutide is a GLP-1 receptor agonist that lowers blood sugar, supports weight loss, and reduces cardiovascular risk in type 2 diabetes.

How it works

It mimics the GLP-1 hormone, boosting meal-time insulin release, reducing glucagon, slowing stomach emptying, and promoting satiety.

Common uses

• Weekly injection (Ozempic) or daily tablet (Rybelsus) for type 2 diabetes
• Reducing major cardiovascular events in high-risk patients
• Weight management when combined with diet and activity

Monitoring & Safety

• Labs: Follow hba1c and glucose to titrate safely.
• Nausea is common early; rare risks include pancreatitis or gallbladder issues.

Dosing (简要)

• Weekly injection starts low and increases gradually; oral form taken once daily on an empty stomach with water.
• Dose escalations every 4 weeks help limit stomach upset.

Drug interactions

• Slower stomach emptying can affect absorption of other oral drugs; separate critical meds when advised.
• Added to insulin or sulfonylureas may require lowering those doses to avoid hypoglycemia.

Patient tips

• Eat smaller, lower-fat meals to ease nausea during titration.
• If you miss a weekly dose, take within 5 days; otherwise skip and resume schedule.
• Continue lifestyle changes for best weight and glucose outcomes.

When to contact your doctor

• Severe abdominal pain with or without vomiting.
• Signs of gallbladder trouble: right-sided pain, fever, yellowing skin.
• Persistent vomiting or inability to keep fluids down.

Medical Disclaimer: 本内容仅供教育用途，不能替代专业医疗建议。