Rosuvastatin

What is Rosuvastatin?

Rosuvastatin is a potent statin that lowers LDL cholesterol and inflammation markers to reduce cardiovascular risk.

How it works

By inhibiting HMG-CoA reductase, it decreases cholesterol production and upregulates LDL receptors, pulling LDL particles from circulation.

Common uses

• High-intensity therapy for patients at elevated cardiovascular risk
• Mixed dyslipidemia with elevated triglycerides
• Familial hypercholesterolemia

Monitoring & Safety

• Labs: Follow ldl, hdl, total-cholesterol, triglycerides, and liver enzymes alt/ast as clinically indicated.
• Mild muscle aches may occur; serious muscle injury is rare.

Dosing (简要)

• Typical range 5-40 mg once daily; higher doses need closer lab follow-up.
• Can be taken any time of day with or without food.

Drug interactions

• Certain HIV and hepatitis C medicines can increase exposure; dose adjustments may be needed.
• Aluminum or magnesium antacids can lower absorption if taken together; separate by 2 hours.

Patient tips

• Keep taking even when cholesterol numbers improve—benefit comes from long-term use.
• Stay hydrated and report unexpected muscle symptoms.
• Combine with diet changes rich in fiber and low in saturated fats.

When to contact your doctor

• Severe muscle pain, weakness, or dark urine.
• Yellowing of skin/eyes or persistent nausea.
• Allergic swelling or difficulty breathing.

Medical Disclaimer: 本内容仅供教育用途，不能替代专业医疗建议。