Insulin Glargine

What is Insulin Glargine?

Insulin glargine is a long-acting insulin that provides steady basal coverage for people with diabetes.

How it works

After injection, glargine forms microprecipitates in the subcutaneous tissue, releasing insulin slowly over about 24 hours to keep glucose stable between meals and overnight.

Common uses

• Basal insulin in type 1 diabetes alongside mealtime insulin
• Basal insulin for type 2 diabetes when pills are not enough
• Hospital protocols needing stable background insulin

Monitoring & Safety

• Labs: Regular glucose checks and periodic hba1c guide dose adjustments.
• Main risks are low blood sugar and injection site irritation.

Dosing (简要)

• Typically injected once daily at the same time; starting doses vary by weight and prior therapy.
• Titrate every few days based on fasting glucose goals set with your care team.

Drug interactions

• Other glucose-lowering drugs increase hypoglycemia risk.
• Beta blockers may mask shakiness during low blood sugar.

Patient tips

• Rotate injection sites to prevent lumps or lipodystrophy.
• Keep rapid carbohydrate (juice, glucose tablets) nearby for lows.
• Do not mix glargine in the same syringe with other insulins.

When to contact your doctor

• Repeated low blood sugars or severe hypoglycemia requiring help.
• Fasting glucose stays high despite several titrations.
• Signs of allergic reaction at injection sites.

Medical Disclaimer: 本内容仅供教育用途，不能替代专业医疗建议。