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Vitamin LevelsUpdated 2025-12-24Medically Reviewed

Vitamin D (25-OH)

Everything you need to know about Vitamin D (25-OH) levels, including what normal ranges look like and what abnormal results might indicate.

Standard Reference Range

Unit: ng/mL
Male Reference Range
30–100 (sufficient) ng/mL
Female Reference Range
30–100 (sufficient) ng/mL
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Reference ranges may vary slightly between laboratories. Always consult your doctor for interpretation.

What is Vitamin D (25-OH)?

The 25-hydroxy vitamin D level reflects total vitamin D stores from sunlight, diet, and supplements. It is the best screening test for deficiency.

Key Takeaway

Levels under 20 ng/mL indicate deficiency; 20–29 ng/mL is insufficiency; 30–50 ng/mL is generally adequate.

Why is this test performed?

  • Evaluate bone health and osteoporosis risk
  • Investigate low calcium/phosphorus or high PTH
  • Monitor supplementation therapy

Interpreting Your Results

  • Low: Poor sun exposure, malabsorption, kidney/liver disease, limited diet
  • High: Excess supplementation; rare granulomatous diseases can produce excess active vitamin D

Related Tests

  • Calcium/Phosphorus: Balance with vitamin D
  • PTH: Rises when vitamin D or calcium is low
  • Magnesium: Needed for vitamin D metabolism

Decode your 25-Hydroxy Vitamin D Results

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Vitamin D (25-OH) Levels: Normal Range, High & Low Meaning | WellAlly