Multiple Sclerosis Plaques
Understanding Multiple Sclerosis Plaques found on Brain and Cervical Spine Magnetic Resonance Imaging imaging. Learn what this finding means and what steps to take next.
Radiographic Appearance
Magnetic Resonance Imaging FindingOvoid T2/FLAIR hyperintense lesions oriented perpendicular to ventricles; Dawson’s fingers; active plaques enhance with gadolinium.
Clinical Significance
Demyelinating lesions supporting MS diagnosis when dissemination in time and space is shown.
What are MS Plaques?
Focal demyelinating lesions from multiple sclerosis. MRI criteria (McDonald) require dissemination in time and space.
Imaging Appearance
- Periventricular, juxtacortical, infratentorial, or spinal cord lesions
- Dawson’s fingers extending from ventricles
- Active lesions enhance; chronic lesions may appear black holes on T1
Clinical Significance
- Supports MS diagnosis with clinical attacks or CSF oligoclonal bands
- Lesion load correlates imperfectly with disability
Symptoms
- Visual loss, sensory changes, weakness, imbalance, Lhermitte sign
Diagnosis
- MRI brain and spine with and without contrast
- CSF studies; evoked potentials as adjunct
Treatment
- Disease-modifying therapy to reduce relapses
- High-dose steroids for acute relapses
- Rehab for symptoms
Prognosis
- Variable; early treatment improves long-term outcomes
What Should You Do?
- Complete recommended MRI follow-up.
- Discuss disease-modifying options with neurology.
- Report new neurologic symptoms promptly.
Medical Disclaimer: Educational only; follow neurologist guidance.
Correlate with Lab Results
Doctors often check these blood tests when Multiple Sclerosis Plaques is found on imaging:
Related Imaging Terms
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