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DXA📍 SkeletonUpdated on 2026-01-20Radiology reviewed

Osteoporosis on DXA Scan

Understand Osteoporosis on DXA Scan in Skeleton DXA imaging, what it means, and next steps.

30-Second Overview

Definition

T-scores and Z-scores measuring bone mineral density. T-score ≤ -2.5 indicates osteoporosis; -1.0 to -2.5 indicates osteopenia.

Clinical Significance

DXA (Dual-energy X-ray Absorptiometry) is gold standard for bone density measurement. T-score classification guides treatment decisions. No radiation concerns—equivalent to < 1 day of natural background radiation.

Benign Rate

benignRate

Follow-up

followUp

Imaging Appearance

DXA Finding

T-scores and Z-scores measuring bone mineral density. T-score ≤ -2.5 indicates osteoporosis; -1.0 to -2.5 indicates osteopenia.

Clinical Significance

DXA (Dual-energy X-ray Absorptiometry) is gold standard for bone density measurement. T-score classification guides treatment decisions. No radiation concerns—equivalent to < 1 day of natural background radiation.

Understanding Your Bone Density Test

A bone density test is the standard way to diagnose osteoporosis. Before understanding your results, let's look at why this test is important.

Routine10 million Americans with osteoporosis; 44 million with osteopenia

DXA scan is quick, painless, and uses minimal radiation—equivalent to less than 1 day of natural background radiation

Here's how accurate DXA is at detecting bone problems:

Sensitivity
95%+

Detects low bone mass with high accuracy

Specificity
90%+

Correctly rules out healthy patients

Prevalence
54M Americans affected

Annual new cases

Think of your bones like a savings account—you build up bone density during childhood and young adulthood, then gradually withdraw as you age. A DXA scan measures your current "bone balance" and predicts your fracture risk.


What Is Osteoporosis?

Osteoporosis means "porous bone"—bones become less dense, more brittle, and prone to fracture. You can't feel bone loss happening, which is why screening is important.

How DXA works:

  • Uses two X-ray beams at different energy levels
  • Measures how much X-ray passes through bone (calculates density)
  • Takes about 10-15 minutes, completely painless
  • Usually scans hip and lower spine (lumbar vertebrae)

What the numbers mean:

| T-score | Bone Density | Fracture Risk | Treatment | |---------|--------------|---------------|------------| | ≥ -1.0 | Normal | Low | None needed | | -1.0 to -2.5 | Osteopenia | Moderate | Consider prevention | | ≤ -2.5 | Osteoporosis | High | Treatment usually recommended |

T-score vs Z-score:

  • T-score: Comparison to healthy young adult (age 30) peak bone mass
  • Z-score: Comparison to age-matched peers (used for premenopausal women, men < 50)

How Bone Density Appears on DXA

Let's visualize what healthy bone looks like compared to osteoporotic bone on a DXA scan:

What Healthy Bone Looks Like

DXA image shows bright white areas representing high bone mineral density. T-score is ≥ -1.0. Bone density is within normal range for a healthy young adult. Trabecular (spongy) bone and cortical (hard) bone both appear dense.

What Osteoporosis Looks Like

DXA image shows darker, thinner bone areas representing low bone mineral density. T-score is ≤ -2.5. Bone appears more translucent (less white). Cortical bone is thinned. Vertebral bodies may show compression fractures (wedge-shaped).

Key Findings Pattern

When interpreting your DXA scan, radiologists look for specific patterns that indicate bone health problems:

Key Imaging Findings

1

T-score ≤ -2.5

Bone density 2.5+ standard deviations below young adult mean

Diagnostic of osteoporosis. Treatment recommended to prevent fractures.
2

Vertebral compression fracture

Wedge-shaped or flattened vertebrae visible on DXA or X-ray

Indicates established osteoporosis—fracture has already occurred. Treatment urgent.
3

Rapid bone loss

Significant decrease in T-score compared to prior DXA (≥ 5% per year)

Requires evaluation for secondary causes (hyperparathyroidism, myeloma, malabsorption).

When Your Doctor Orders This Test

Here's a typical scenario where a DXA scan is recommended:

Clinical Scenario

Patient68-year-old
Presenting withRoutine bone density screening due to age (postmenopausal female)
Asymptomatic, screening
ContextNo prior fractures. Taking calcium and vitamin D supplements.
Imaging Indication:Baseline bone density assessment for fracture risk and to guide prevention/treatment decisions.

Screening DXA is recommended for:

  • All women ≥ 65 years
  • Men ≥ 70 years
  • Postmenopausal women < 65 with risk factors
  • Anyone who has fractured a bone after age 50
  • Adults on long-term corticosteroids (≥ 3 months)
  • Anyone with medical conditions associated with bone loss (RA, hyperthyroidism, etc.)

How often: Every 2 years for monitoring, or sooner if risk factors change.


Understanding Your Results

Your T-score falls into one of several categories, each with different implications for your bone health:

What Else Could It Be?

Normal (T-score ≥ -1.0)Low

Bone density within 1 standard deviation of young adult mean. Fracture risk low. Continue preventive measures (calcium, vitamin D, weight-bearing exercise).

Osteopenia (T-score -1.0 to -2.5)Moderate

Bone density 1-2.5 SD below young adult mean. Fracture risk increased. Lifestyle changes, calcium/vitamin D, possibly medication depending on FRAX score.

Osteoporosis (T-score ≤ -2.5)Moderate

Bone density > 2.5 SD below young adult mean. Fracture risk significantly increased. Treatment with bisphosphonates or other medications usually recommended.

Secondary osteoporosisModerate

T-score worse than expected for age, or rapid bone loss. Needs lab workup: PTH, vitamin D, thyroid function, protein electrophoresis, celiac screening.


FRAX: Your Fracture Risk Score

Your doctor may use the FRAX tool to estimate your 10-year fracture risk:

| Risk Factor | Why It Matters | |-------------|----------------| | Age | Risk increases each year after menopause | | Low bone mass (T-score) | Lower T-score = higher fracture risk | | Previous fracture | Having had one fracture doubles risk of another | | Parent had hip fracture | Family history increases risk | | Smoking | Current smokers have higher fracture risk | | Glucocorticoids | Long-term steroid use increases risk | | Rheumatoid arthritis | Chronic inflammation accelerates bone loss | | Secondary causes | Diabetes, osteogenesis imperfecta, etc. | | Alcohol > 2 drinks/day | Excessive alcohol increases fracture risk |

Treatment threshold: Medication may be recommended if your 10-year major osteoporotic fracture risk is ≥ 20% or hip fracture risk ≥ 3%.


How Accurate Is DXA?

The evidence supporting DXA as the gold standard for bone density measurement is strong:

Precision: 1-2% (hip), 2-3% (spine)

DXA is highly precise—small changes (1-3%) can be reliably detected. This allows monitoring response to treatment over time. The least significant change (LSC) is the smallest change that indicates real bone change, not measurement error.

Source: International Society for Clinical Densitometry
T-score predicts fracture risk

For each 1 standard deviation decrease in T-score, fracture risk approximately doubles. A T-score of -2.5 has about 4-5x higher fracture risk than a T-score of -0.5. This relationship holds for hip, spine, and wrist fractures.

Source: National Osteoporosis Foundation
Radiation: < 1 µSv (minimal)

DXA uses very low radiation—less than 1 microsievert. For comparison, a chest X-ray is about 100 µSv, natural background radiation is about 3 mSv/year (3000 µSv/year) from cosmic rays and radon. DXA is safe for repeated testing.

Source: U.S. Preventive Services Task Force
🧠 Knowledge Check

Your DXA report shows T-score of -2.1 at the hip. What does this mean?

Click an option to select your answer


What Happens Next?

If your DXA shows abnormal bone density, here's the typical care pathway:

What Happens Next?

Receive your results

Within 1-2 weeks

Your doctor will review T-scores, Z-scores, and compare to prior studies if available. You'll discuss fracture risk based on age, T-score, and other risk factors.

Laboratory workup (if osteoporosis or unexplained bone loss)

Within 2-4 weeks

Blood tests to identify secondary causes: CBC, CMP, 25-OH vitamin D, PTH, TSH, serum protein electrophoresis, urine calcium. This guides treatment.

Treatment discussion

Within 1 month of diagnosis

Options include bisphosphonates (alendronate), RANK ligand inhibitor (denosumab), anabolic agent (teriparatide), or selective estrogen receptor modulator (raloxifene). Discuss risks and benefits.

Lifestyle modifications

Immediate and ongoing

Calcium 1200 mg/day + Vitamin D 800-1000 IU/day. Weight-bearing exercise (walking, jogging, strength training) 3-4x/week. Fall prevention: home safety, balance exercises, vision check.

Follow-up DXA

1-2 years after starting treatment

Repeat DXA to monitor treatment response. Stable or increasing T-score indicates effective treatment. Significant loss may require change in therapy.

When to Seek Immediate Care

Seek medical attention if you experience:

  • Sudden severe back pain (may indicate compression fracture)
  • Loss of height (> 1.5 inches = 4 cm)
  • Development of kyphosis (dowager's hump) or spinal curve
  • Fracture from minor trauma (shouldn't break bones from sneezing, coughing, or minor falls)

Frequently Asked Questions

Do I need to undress for a DXA scan?

You'll need to remove clothing with metal (zippers, buttons, underwire bras). Wear loose, comfortable clothes without metal. You may be asked to change into a gown. Remove all jewelry.

Should I stop calcium supplements before the scan?

No, unlike some other tests, DXA is not affected by recent calcium intake. Continue your usual diet and supplements. However, tell the technologist about any recent imaging studies with contrast (barium studies, CT with contrast)—wait 7-14 days after these.

Can I have DXA if I'm pregnant?

DXA uses X-rays, so it's generally avoided during pregnancy unless medically necessary. Tell your doctor if you're pregnant or might be pregnant. For most women, DXA can wait until after pregnancy.

What if I have metal implants?

Hip replacements, spinal hardware, or surgical clips can interfere with DXA measurements. The technologist will avoid scanning those areas and use alternative sites (forearm, other hip) if needed.

How often should I repeat DXA?

  • Every 2 years for monitoring osteopenia or osteoporosis
  • Every 1-2 years after starting treatment to monitor response
  • Every 5-10 years if normal and low risk
  • More frequently if on long-term steroids or high-risk medications

References

Medical References

This content is referenced from authoritative medical organizations:

  • 1.
    ISCD Official Positions on Bone Density MeasurementInternational Society for Clinical Densitometry(2023)View
  • 2.
    Clinician's Guide to Prevention and Treatment of OsteoporosisNational Osteoporosis Foundation(2023)View
  • 3.
    Osteoporosis Screening RecommendationsU.S. Preventive Services Task Force(2022)View
⚠️ This content is for informational purposes only and does not constitute medical advice. Consult a healthcare provider for personalized diagnosis and treatment.

Medical Disclaimer: This information is for educational purposes. Always discuss your imaging results with your healthcare provider for personalized medical advice.

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