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Blood Pressure Comparison

ACE Inhibitors (Angiotensin-Converting Enzyme Inhibitors) vs ARBs (Angiotensin II Receptor Blockers)

A detailed comparison of ACE Inhibitors (Angiotensin-Converting Enzyme Inhibitors) and ARBs (Angiotensin II Receptor Blockers) to help you understand the differences and make informed decisions about your blood pressure treatment.

What They Have in Common

  • Both are used to treat: Hypertension, Diabetic kidney protection
  • Both require monitoring: creatinine, potassium
  • Both require prescription
  • Both should be taken as directed by your doctor

Key Differences

ACE Inhibitors (Angiotensin-Converting Enzyme Inhibitors)

  • Dosing: ACE Inhibitors (Angiotensin-Converting Enzyme Inhibitors): Once or twice daily, can be taken with or without food. ARBs (Angiotensin II Receptor Blockers): Once daily, with or without food.
  • Time to effect: Blood pressure reduction seen within hours; full effect in weeks
  • Form: Tablets: Various strengths; Enalapril also available as oral solution

ARBs (Angiotensin II Receptor Blockers)

  • Dosing: ACE Inhibitors (Angiotensin-Converting Enzyme Inhibitors): Once or twice daily, can be taken with or without food. ARBs (Angiotensin II Receptor Blockers): Once daily, with or without food.
  • Time to effect: 2-4 hours for BP effect; full benefit 2-4 weeks
  • Form: Tablets: 25mg, 50mg, 100mg, 150mg, 300mg, 320mg, 40mg, 80mg

Side Effects

ACE Inhibitors (Angiotensin-Converting Enzyme Inhibitors) may cause: Dry cough, Dizziness when standing, Fatigue. ARBs (Angiotensin II Receptor Blockers) may cause: Dizziness or lightheadedness, Tiredness or weakness, Mild stomach upset.

When to Choose ACE Inhibitors (Angiotensin-Converting Enzyme Inhibitors)

  • 1.You have diabetes with kidney involvement
  • 2.You've had a heart attack (ACE inhibitors have proven survival benefit)
  • 3.Cost is a consideration (ACE inhibitors are often generic and less expensive)

When to Choose ARBs (Angiotensin II Receptor Blockers)

  • 1.You developed a cough on ACE inhibitors
  • 2.You have had angioedema (swelling) with ACE inhibitors
  • 3.You prefer a medication with fewer cough-related side effects

Important Considerations

  • Both medications require a prescription and medical supervision
  • Individual response varies - what works for others may not work for you
  • Never switch medications without consulting your doctor
  • Both medications have serious warnings - discuss with your doctor
  • Regular lab monitoring may be required
  • Tell your doctor about all medications and supplements you take

Talk to Your Doctor

This comparison is for educational purposes. Only your healthcare provider can determine which medication is right for you.

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This information is for educational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before starting, stopping, or changing any medication.
ACE Inhibitors (Angiotensin-Converting Enzyme Inhibitors) vs ARBs (Angiotensin II Receptor Blockers): Complete Comparison | WellAlly